Fumer du cannabis augmenterait le risque de cancer des testicules

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Fumer du cannabis augmenterait le risque de cancer des testicules
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"But the researchers only interviewed a relatively small number of men.

"So before we can reach any firm conclusions about whether this is a cause-and-effect relationship, rather than a statistical blip, the result needs to be replicated in a much larger study."

http://www.maxisciences.com/cannabis/fumer-du-cannabis-augmenterait-le-r...

Fumer du cannabis augmenterait le risque de cancer des testicules
Info rédaction, publiée le 11 février 2009

États-Unis - Une étude menée par le Centre de recherche sur le cancer de Seattle montre que les fumeurs de cannabis risquent davantage de développer un cancer des testicules d’une forme plus agressive.

Les fumeurs réguliers de cannabis ont 70 % de risques supplémentaires de développer un cancer des testicules. L’équipe du Dr Stephen Schwartz a interrogé 369 hommes âgés de 18 à 44 ans atteints de cette maladie et comparé leurs réponses avec celles de 979 hommes de la même tranche d’âge mais non-atteints. En dehors de tous les autres facteurs, comme l’alcool ou la cigarette, le cannabis émerge comme une cause possible significative.

Ce lien est particulièrement concret pour le cancer non-séminomateux des testicules, un cancer qui évolue rapidement, qui touche la tranche d’âge concernée par l’étude et dont le pronostic vital est moins bon. Les chercheurs pensent que la marijuana interrompt le fonctionnement d’une enzyme produite par le corps, celle-ci ayant un effet protecteur contre le cancer.

Cette étude est la première à montrer le lien entre consommation régulière de cannabis et cancer des testicules. Le Dr Schwartz souhaite confirmer ces premiers résultats et comprendre pourquoi cette drogue met les hommes en danger

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http://www.telegraph.co.uk/science/science-news/4566251/Cannabis-could-c...
Cannabis could cause testicular cancer - study
Smoking cannabis could increase the risk of developing testicular cancer by 70 per cent, scientists have warned.

By John Bingham
Published: 8:42AM GMT 09 Feb 2009

A study in the US found a link between soaring marijuana use and increased incidence of the disease for the first time.

The link is limited to the aggressive nonseminoma types of testicular cancer which strike earlier than other varieties, affecting men aged between 20 and 35.

Researchers led by Dr Stephen Schwartz of the Fred Hutchinson Cancer Research Center in Seattle noticed that the rate at which the disease has spread in US, Canada, Europe, Australia and New Zealand since the 1950s appeared to follow the increase in cannabis use closely.

"In the absence of more certain information, a decision to smoke marijuana recreationally means that one is taking a chance on one's future health," said Dr Schwartz.

"In the absence of more certain information, a decision to smoke marijuana recreationally means that one is taking a chance on one's future health," said Dr Schwartz.

The team interviewed 369 men with testicular cancer, in the Seattle area - mostly in their 20s and 30s - about their history of marijuana use.

They then compared their responses with those from just under 1,000 men without the disease from a similar area and age group.

Even after other "lifestyle" factors such as smoking and drinking as well as risks such as a family history of the disease, cannabis use emerged as a significant possible cause, the study published in the journal Cancer concluded.

Regular or long-term cannabis smokers appeared twice as likely to develop the disease as those who had never used the drug.

Being a regular marijuana smoker at the time of diagnosis was associated with a 70% increased risk.

The team suggested that marijuana use may disrupt the working of a chemical produced by the body which is thought to have a protective effect against cancer.

But they emphasised that their results were not definitive and called for further study.

"Our study is not the first to suggest that some aspect of a man's lifestyle or environment is a risk factor for testicular cancer, but it is the first that has looked at marijuana use," said Dr Schwartz.

Henry Scowcroft, of Cancer Research UK, said: "As the researchers themselves point out, this is the first inkling that there is any association between chronic marijuana use and testicular cancer.

"But the researchers only interviewed a relatively small number of men.

"So before we can reach any firm conclusions about whether this is a cause-and-effect relationship, rather than a statistical blip, the result needs to be replicated in a much larger study."

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